Peritoneal dialysis
This information is for people with autosomal dominant polycystic kidney disease (ADPKD) who have or are nearing kidney failure. It’s also for their families and friends. It explains how you prepare for peritoneal dialysis and how you’ll do swap fluids. It also looks at side effects and risks, monitoring and travel.
See also our webpages introducing dialysis and about haemodialysis.
Options for the treatment of kidney failure
If you have kidney failure, your treatment options may include:
- a kidney transplant
- dialysis (haemodialysis or peritoneal dialysis)
- supportive medicines and care only
This page is on peritoneal dialysis. To understand your other options, see our pages on Kidney transplants in ADPKD and an introduction to dialysis.
Preparing to have peritoneal dialysis
If you choose to have peritoneal dialysis, the first step is a home visit to check you have all the facilities needed at home.
You’ll need a surgical procedure at least 2 weeks before starting peritoneal dialysis. A medical nephrologist or surgeon will fix a tube called a catheter through the skin below your belly button into your abdomen (tummy).
The catheter will go into your peritoneum, which is a membrane that surrounds your organs and bowels. You’ll have the catheter long term (unless you stop having peritoneal dialysis). It has a cap on it.
You’ll have a local or general anaesthetic before the surgical procedure to fit the catheter. The procedure can usually be done in one day (meaning you won’t need to stay at hospital overnight). You’ll be given antibiotics to reduce your chance of getting an infection.
The nursing team will teach you about peritoneal dialysis before you get started.
Peritoneal dialysis sessions
Once you start peritoneal dialysis you’ll have dialysis fluid (dialysate) in your abdomen most of the time. Over a few hours, waste and fluid in your blood will travel through tiny blood vessels in your peritoneum into the dialysis fluid.
You, a relative, caregiver or visiting technician will drain out the old dialysis fluid and replace it with fresh fluid using your catheter (see picture).
There are two ways of refreshing dialysis fluid:
- Automated peritoneal dialysis: You’ll use a machine to automatically swap the fluids during the night while you sleep.
- Continuous ambulatory peritoneal dialysis: You, a relative, caregiver or technician will do a fluid swap about 4 times a day. It takes about 30–45 minutes each time.
Experts think these two types of peritoneal dialysis work equally well, although there’s not been much research comparing them. Automated peritoneal dialysis is the more common choice.
Your dialysis team will be on hand for advice and care when you need.
Side effects and risks
Peritoneal dialysis can make you feel tired and sick. It can also lead to low blood pressure that can make you feel dizzy or lightheaded. Some people find it uncomfortable to have a peritoneal catheter, to have fluid in their abdomen or to do the fluid swaps.
Let your nursing team know if you get any of these problems as changes to your dialysis schedule or the fluid ingredients can help.
You’ll probably need to take laxatives daily to prevent constipation (difficulty pooing). This is because constipation can move or squash your catheter, stopping it working well. Laxatives make your poo softer and you might need the toilet more urgently.
If you have peritoneal dialysis, there’s a risk of:
- getting an infection around your catheter or in your peritoneum (known as peritonitis)
- getting a hernia, meaning part of your bowel bulges through your tummy muscles under the skin
- the catheter becoming blocked, not draining well or leaking
- changes to your peritoneum that require treatment
You’ll need to keep your catheter clean to reduce the chance of infection. Your dialysis team will explain the signs of infection to look out for. If you have diverticular disease and use peritoneal dialysis, you might be more likely to get peritonitis.
If you get an infection, you’ll need antibiotics either at home or in hospital. If the infection doesn’t clear, you might need a procedure to adjust or replace parts of your catheter. A nurse can do this for you. You might need to have haemodialysis until the infection clears.
If you get a hernia, you may need surgery to correct this.
If your catheter becomes blocked, a nurse can usually unblock it for you. If it keeps leaking, a radiologist can use scans to see why. Some leaks get better on their own — you might need to swap to haemodialysis while it settles. If the leak continues, your catheter might need adjusting or replacing.
Some people having peritoneal dialysis get a thicker or harder peritoneum covered in calcium. This is called encapsulating peritoneal sclerosis and can make you unwell. You’re likely to need nutritional supplements by mouth or into a vein until you’re well enough to eat again.
Encapsulating peritoneal sclerosis can be hard to treat so you may need to switch to having haemodialysis.
Monitoring
You’ll have regular monitoring (usually at least every 6 months) to check peritoneal dialysis is working well to clean your blood. You might need check-ups more often if your kidney function is very low. You’ll also have check-ups of your peritoneum.
Check-ups are a chance for you and your dialysis team to review any side effects and discuss how dialysis is impacting your life. They might be able to suggest changes, treatments or support to help.
You might be able to do some of these check-ups over the phone or on video call rather than visiting the clinic.
Travel
You can do your fluid swaps anywhere clean and light with a sink to wash your hands. You can go on holiday or overnight stays — just take enough supplies and follow your dialysis routine.
For more information, see Kidney Care UK’s guide Dialysis Away From Base. You can get help organizing dialysis away from home through their free service called Dialysis Freedom.
More from the PKD Charity
Information and support from others
- Kidney Research UK has a guide to help you decide which type of dialysis is right for you.
- Kidney Care UK has information on dialysis, as well as a guide to travelling while on dialysis and a free service (Dialysis Freedom) to help you organize dialysis away from home.
- Oxford University Hospitals has a guide on peritoneal dialysis. Services from other hospitals may differ.
Further information
All of our publications are based on references but these are removed for ease of reading on our webpages. A version of this webpage with references included is available upon request by emailing [email protected].
Authors and contributors
Written by Hannah Bridges, PhD, Independent Medical Writer at HB Health Comms Limited. Expert review by Matthew Gittus, PhD Fellow,
Sheffield Kidney Institute, University of Sheffield.
With thanks to all those affected by ADPKD who contributed to this publication.
Ref No: ADPKD.PD.V1.0
© PKD Charity 2025
First published: June 2025
Due to be medically reviewed: June 2028
Disclaimer: This information is primarily for people in the UK. We have made every effort to ensure that the information we provide is correct and up to date. However, it is not a substitute for professional medical advice or a medical examination. We do not promote or recommend any treatment. We do not accept liability for any errors or omissions. Medical information, the law and government regulations change rapidly, so always consult your GP, pharmacist or other medical professional if you have any concerns or before starting any new treatment.
If you don't have access to a printer and would like a printed version of this information sheet, or any other PKD Charity information, call the PKD Charity Helpline on 0300 111 1234 (weekdays, 9am–5pm) or email [email protected]
The PKD Charity Helpline offers confidential support and information to anyone affected by PKD, including family, friends, carers, newly diagnosed or those who have lived with the condition for many years.
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